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![]() ![]() Conduit arteries including aortas and carotid arteries were obtained from male C57BL/6J mice for ex vivo treatment with risk factors (high glucose or tunicamycin) and coptisine. ![]() Coptisine reduces inflammatory responses and improves glucose tolerance nevertheless, whether coptisine has vasoprotective effect in diabetes is not fully characterized. Coptisine is the major bioactive protoberberine alkaloid found in Rhizoma Coptidis.
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